1-Boc-3-hydroxypiperidine CAS 85275-45-2

1. Description

1-Boc-3-hydroxypiperidine (CAS 85275-45-2) is a key heterocyclic building block used extensively in pharmaceutical synthesis. As an N-Boc protected piperidine derivative containing a hydroxyl group, it serves as a crucial intermediate for constructing complex Active Pharmaceutical Ingredients (APIs). Its utility lies in providing a modifiable piperidine scaffold essential for various therapeutic agents.

2. Properties Table

Property Value
Product Name 1-Boc-3-hydroxypiperidine
CAS Number 85275-45-2
Chemical Class N-Protected Piperidine Alcohol
Appearance White to off-white crystalline solid
Molecular Formula
Molecular Weight
Melting Point (Typical for racemic)
Solubility Soluble in DCM, Ethyl Acetate, Methanol
Purity (Assumed) (HPLC)

3. Usage

  • Intermediate in the synthesis of APIs containing the 3-hydroxypiperidine moiety, common in CNS-active drugs.
  • Used as a building block for developing kinase inhibitors and antiviral agents.
  • Essential precursor in multi-step organic synthesis pathways for novel drug candidates targeting various receptors.

4. Packaging & Transportation

Supplied in securely sealed, airtight containers, often amber glass or HDPE bottles, to prevent moisture uptake. Packaged and shipped in compliance with standard chemical transport regulations (e.g., IATA, DOT); handle according to Safety Data Sheet (SDS).

5. Storage

Store in a cool (), dry, well-ventilated area away from incompatible materials. Keep container tightly sealed; storage under inert gas (Nitrogen) recommended for optimal stability.

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