2-Aminoacetophenone CAS 551-93-9

Product Details

Overview
2-Aminoacetophenone, also known as 2′-Aminoacetophenone or 2-Acetylaniline, is a chemical compound with the molecular formula C8H9NO and CAS number 551-93-9. It is primarily used as an intermediate in pharmaceutical synthesis and has emerging roles in diagnostics.

Chemical Properties
This compound has the following specifications:

• Molecular Weight: 135.16 g/mol
• Assay: ≥98%
• Refractive Index: n 20/D 1.614 (lit.)
• Boiling Point: 85-90 °C/0.5 mmHg (lit.)
• Density: 1.112 g/mL at 25 °C (lit.)
• Storage Temperature: 2-8°C

These properties make it suitable for laboratory and industrial applications, ensuring stability and reliability.

Applications and Uses
2-Aminoacetophenone is likely used as a parent compound for developing stimulant and entactogen drugs, which are significant in pharmaceutical innovation. It also serves as a biomarker to detect Pseudomonas aeruginosa infections, particularly in the lungs of cystic fibrosis patients, aiding in diagnostic efforts. Additionally, it has applications in flavors and fragrances, though its pharmaceutical uses are more prominent.

Benefits

• High purity (≥98%) ensures consistent results in research and development.
• Its versatility allows use in both drug synthesis and diagnostic tools, offering multiple avenues for utilization.
• Sourced from reputable manufacturers, it meets high-quality standards, making it a reliable choice for pharmaceutical applications.

An unexpected detail is its dual role in both pharmaceuticals and the food industry, highlighting its broad applicability beyond traditional drug development.

Product Details and Specifications

2-Aminoacetophenone, also referred to as 2′-Aminoacetophenone or 2-Acetylaniline, is a chemical compound identified by the CAS number 551-93-9 and molecular formula C8H9NO. It is a key intermediate in pharmaceutical synthesis, with additional applications in diagnostics and other industries. The compound’s chemical properties include:

Property	Value
Molecular Weight	135.16 g/mol
Assay	≥98%
Refractive Index	n 20/D 1.614 (lit.)
Boiling Point	85-90 °C/0.5 mmHg (lit.)
Density	1.112 g/mL at 25 °C (lit.)
Storage Temperature	2-8°C

These specifications ensure the compound’s suitability for high-precision applications, particularly in research and development. The storage temperature of 2-8°C indicates the need for controlled conditions to maintain stability, which is critical for pharmaceutical use.

Applications and Pharmaceutical Relevance

The compound’s pharmaceutical applications are multifaceted. Research suggests it serves as a parent compound for stimulant and entactogen drugs, as noted in Wikipedia, where it is described as a norepinephrine–dopamine releasing agent (NDRA). This role positions it as essential for drug development, particularly in synthesizing compounds with stimulant properties.

Beyond pharmaceuticals, the compound has applications in flavors and fragrances, where it is described as a key volatile flavor component of masa corn flour products with a grape-like odor. This dual utility is an unexpected detail, extending its relevance to the food industry, though the focus here is on its pharmaceutical potential.

Uses and Benefits

The benefits of 2-Aminoacetophenone in pharmaceutical contexts include:

• High Purity: With an assay of ≥98%, it ensures consistent and reliable results in research, crucial for drug synthesis and testing.
• Versatile Applications: Its role as both a synthetic intermediate and a biomarker provides multiple avenues for utilization, enhancing its value in both development and diagnostics.
• Reliable Source: Sourced from reputable suppliers like Sigma-Aldrich, it meets high-quality standards, ensuring compliance with pharmaceutical regulations.

These benefits make it an attractive option for researchers and companies looking to innovate in drug development and diagnostic tools.