2′,3′-Di-O-acetyl-5′-deoxy-5-fuluro-D-cytidine CAS 161599-46-8

Details

  • Chemical Name: 2′,3′-di-O-acetyl-5′-deoxy-5-fluorocytidine
  • Common Designation: Capecitabine Intermediate
  • CAS Number: 161599-46-8
  • Molecular Formula: C₁₃H₁₆FN₃O₆
  • Appearance: Typically White to Off-White Crystalline Powder or Solid
  • Purity: [Specify available purity levels, e.g., ≥98%, ≥99%]
  • Properties

    Property Value
    Molecular Weight 345.28 g/mol
    Appearance White to Off-White Solid/Powder
    Purity [Specify Available Purity %]
    Solubility [Specify Solvents, e.g., Soluble in DMSO, DMF, Methanol; check water solubility]
    Melting Point [Specify Range if known, e.g., Approx. 135-140 °C – Confirm with CoA]
    Storage Condition Recommended [Specify, e.g., 2-8°C or Controlled Room Temp], Protect from Light
    Stability May be sensitive to moisture and light

    Usage

    The exclusive and critical application of 2′,3′-di-O-acetyl-5′-deoxy-5-fluorocytidine is its function as a key intermediate in the chemical synthesis pathway for producing Capecitabine (CAS 154361-50-9). Capecitabine is an indispensable antineoplastic agent (a prodrug converted to 5-Fluorouracil in vivo). This intermediate is therefore essential for pharmaceutical manufacturers engaged in the development and large-scale production of Capecitabine API.

    Packaging and Transportation

    [Your Company Name] provides 2′,3′-di-O-acetyl-5′-deoxy-5-fluorocytidine packaged with utmost care to preserve product quality, stability, and integrity, conforming to pharmaceutical intermediate standards. Typical packaging solutions include:

    • [Specify packaging type 1, e.g., Amber glass bottles with secure caps]
    • [Specify packaging type 2, e.g., Double polyethylene bags within fiber or plastic drums]
    • [Specify packaging type 3, e.g., Foil-lined bags, potentially under inert gas]

    All transportation is carried out in strict compliance with relevant national and international regulations governing the shipment of chemical substances and pharmaceutical intermediates. Please consult the product Safety Data Sheet (SDS) for detailed transport classification and handling guidelines.

    Storage

    Proper storage is critical to maintain the quality and efficacy of 2′,3′-di-O-acetyl-5′-deoxy-5-fluorocytidine:

    • Store in a cool, dry, and dark environment.
    • Keep containers tightly sealed at all times to prevent exposure to air, moisture, and light.
    • The recommended storage temperature is typically [Specify temperature range, e.g., 2-8°C or specify controlled room temperature based on stability data].
    • Store separately from incompatible substances.
    • Always adhere to the detailed storage, handling, and safety instructions provided in the Safety Data Sheet (SDS).

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