1. Description
1-Boc-3-hydroxypiperidine (CAS 85275-45-2) is a key heterocyclic building block used extensively in pharmaceutical synthesis. As an N-Boc protected piperidine derivative containing a hydroxyl group, it serves as a crucial intermediate for constructing complex Active Pharmaceutical Ingredients (APIs). Its utility lies in providing a modifiable piperidine scaffold essential for various therapeutic agents.
2. Properties Table
| Property | Value |
| Product Name | 1-Boc-3-hydroxypiperidine |
| CAS Number | 85275-45-2 |
| Chemical Class | N-Protected Piperidine Alcohol |
| Appearance | White to off-white crystalline solid |
| Molecular Formula | |
| Molecular Weight | |
| Melting Point | (Typical for racemic) |
| Solubility | Soluble in DCM, Ethyl Acetate, Methanol |
| Purity (Assumed) | (HPLC) |
3. Usage
- Intermediate in the synthesis of APIs containing the 3-hydroxypiperidine moiety, common in CNS-active drugs.
- Used as a building block for developing kinase inhibitors and antiviral agents.
- Essential precursor in multi-step organic synthesis pathways for novel drug candidates targeting various receptors.
4. Packaging & Transportation
Supplied in securely sealed, airtight containers, often amber glass or HDPE bottles, to prevent moisture uptake. Packaged and shipped in compliance with standard chemical transport regulations (e.g., IATA, DOT); handle according to Safety Data Sheet (SDS).
5. Storage
Store in a cool (), dry, well-ventilated area away from incompatible materials. Keep container tightly sealed; storage under inert gas (Nitrogen) recommended for optimal stability.