Sodium Monofluorophosphate CAS 10163-15-2

Description

Sodium Monofluorophosphate (SMFP), CAS 10163-15-2, is an inorganic chemical compound with the formula . It is primarily recognized for its effectiveness as an anti-caries agent, meaning it helps prevent tooth decay. SMFP functions by releasing fluoride ions, which integrate into the tooth enamel, making it more resistant to acid attacks from plaque bacteria and sugars in the mouth. This process aids in the remineralization of tooth enamel and inhibits demineralization. Due to these properties, Sodium Monofluorophosphate is a common active ingredient in various dental care products, particularly toothpastes and some mouthwashes. It is valued for its stability and compatibility with other common toothpaste ingredients.

Properties

Property Value
CAS Number 10163-15-2
Molecular Formula
Molecular Weight 143.95 g/mol
Appearance White, odorless crystalline powder or crystals
Solubility Soluble in water; insoluble in alcohol
pH (1% solution) Typically 6.5 – 8.0
Melting Point Approximately (1157 ) (decomposes)
Fluoride Content Theoretically 13.19% (often specified as available fluoride)
Typical Grades USP (United States Pharmacopeia), NF (National Formulary), EP (European Pharmacopoeia), Technical Grade
Stability Relatively stable under normal storage conditions, especially in formulated products.

Usage

Sodium Monofluorophosphate’s primary and most well-known application is in oral hygiene products for the prevention of dental caries (cavities):

  • Dental Care Products:
    • Toothpaste: It serves as a fluoride source to strengthen tooth enamel and prevent decay. It is compatible with many abrasive systems used in toothpaste.
      • Example: A key active ingredient in numerous over-the-counter and prescription fluoride toothpastes.
    • Mouthwashes/Rinses: Though less common than sodium fluoride in rinses, it can be used in some formulations to provide anti-cavity benefits.
      • Example: Certain therapeutic oral rinses aimed at caries prevention.
    • Other Dental Preparations: May be included in other professional or consumer dental products designed to deliver fluoride to the teeth.

While its dominant use is in dental care, there might be limited, niche industrial applications, though these are far less common:

  • Metal Surface Treatment: Sometimes used in certain specialized metal cleaning or treatment formulations.
  • Chemical Intermediate: Potentially used in the synthesis of other chemical compounds.

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