R-Alpha Lipoic Acid supplier (R)-(+)-1,2-Dithiolane-3-pentanoic acid CAS 1200-22-2

Product Description

(R)-(+)-1,2-Dithiolane-3-pentanoic acid, also widely known as R-Alpha Lipoic Acid (R-ALA), is the naturally occurring, biologically active enantiomer of alpha-lipoic acid. It is a potent organosulfur compound derived from caprylic acid. Functioning as a vital cofactor in enzymatic reactions, R-ALA plays a crucial role in aerobic metabolism and is recognized for its powerful antioxidant properties, capable of neutralizing a wide range of free radicals in both water-soluble and fat-soluble domains within the cell. This makes it a valuable compound in various biochemical and pharmaceutical research applications, as well as in the formulation of high-quality dietary supplements.

Product Properties

Property Value
Chemical Name (R)-(+)-1,2-Dithiolane-3-pentanoic acid
Common Name R-Alpha Lipoic Acid, R-ALA, Thioctic acid (R-form)
CAS Number 1200-22-2
Molecular Formula C8H14O2S2
Molecular Weight 206.33 g/mol
Appearance Typically a yellow crystalline powder
Solubility Soluble in organic solvents like ethanol, DMSO, and dimethyl formamide; sparingly soluble in water.
Melting Point Approximately 48-52 °C (may vary depending on purity)
Optical Rotation Specific rotation is positive
Purity Available in various purity grades (e.g., >98%, >99%)
Storage Store in a cool, dry place, away from light and moisture.

Product Usage

(R)-(+)-1,2-Dithiolane-3-pentanoic acid is primarily utilized for its significant antioxidant capabilities and its role in energy metabolism. Its applications include:

  • Pharmaceutical Research: Investigated for its potential therapeutic effects in conditions related to oxidative stress, such as diabetic neuropathy, neurodegenerative disorders, and liver diseases.
  • Dietary Supplements: A key ingredient in high-quality nutritional supplements aimed at supporting antioxidant defense, improving insulin sensitivity, and promoting overall cellular health.
  • Cosmeceuticals: Incorporated into skincare formulations for its antioxidant and anti-aging properties, helping to protect skin from environmental damage.
  • Chemical Synthesis: Used as a chiral building block or intermediate in the synthesis of other complex molecules.
  • Veterinary Products: Employed in supplements for animal health, particularly for its antioxidant benefits.

As a supplier, providing high-purity (R)-(+)-1,2-Dithiolane-3-pentanoic acid caters to manufacturers in the pharmaceutical, nutraceutical, and cosmetic industries seeking a reliable source of this biologically active compound.

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