Product Description
N,N,N’,N’-Tetramethylethylenediamine, commonly known as TMEDA or TEMED, is an aliphatic tertiary amine. It appears as a colorless to slightly yellow liquid with a characteristic strong, fishy, or amine-like odor. TMEDA is highly soluble in water and many organic solvents. This compound is widely recognized for its utility as a chelating ligand for various metal ions, particularly lithium, and as a catalyst or accelerator in polymerization reactions and organic synthesis.
Product Properties
Property Value Chemical Formula C₆H₁₆N₂ Molar Mass 116.21 g/mol Appearance Colorless to slightly yellow liquid Odor Strong, fishy, amine-like Density Approximately 0.775 g/mL at 20 °C Melting Point Approximately -55 °C Boiling Point Approximately 120-122 °C Flash Point Approximately 10 °C (50 °F) – Highly Flammable Solubility in Water Miscible Refractive Index Approximately 1.4179 at 20 °C Common Synonyms TEMED, 1,2-Bis(dimethylamino)ethane Product Usage
N,N,N’,N’-Tetramethylethylenediamine (TMEDA) is a versatile compound with several key industrial and laboratory applications. It is extensively used as a ligand in organometallic chemistry, particularly to activate organolithium reagents by breaking down their aggregate structures, thereby increasing their reactivity and solubility. TMEDA is also a crucial catalyst, often used in conjunction with ammonium persulfate (APS), to promote the polymerization of acrylamide and bis-acrylamide in the preparation of polyacrylamide gels for electrophoresis (e.g., SDS-PAGE). Furthermore, it serves as a catalyst or curing agent in the production of polyurethanes and epoxy resins, and as an intermediate in various organic syntheses.
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