Product Description:
L-Phenylglycine, CAS 2935-35-5, is an optically active amino acid possessing the L-configuration. It functions as a vital chiral building block and indispensable intermediate within the pharmaceutical industry, particularly renowned for its role in the synthesis of semi-synthetic beta-lactam antibiotics and other enantiomerically pure active pharmaceutical ingredients (APIs).
Product Properties:
Property Value Chemical Name L-Phenylglycine IUPAC Name (S)-2-Amino-2-phenylacetic acid Other Names L-(+)-α-Aminophenylacetic acid; (S)-Phenylglycine CAS Number 2935-35-5 Molecular Formula C<sub>8</sub>H<sub>9</sub>NO<sub>2</sub> Molecular Weight 151.16 g/mol Appearance White to off-white crystalline powder Purity Typically ≥99% (pharmaceutical grade) Chirality L-enantiomer ((S)-configuration) Melting Point Approximately 300 °C (decomposes) (May vary) Specific Optical Rotation [α]<sub>D</sub> typically +150° to +160° (c=1, 1M HCl) (May vary by specific conditions/supplier) Solubility Slightly soluble in water; soluble in dilute aqueous acids and alkalis Storage Conditions Store in a cool, dry, well-ventilated place, in a tightly sealed container Product Usage:
L-Phenylglycine (CAS 2935-35-5) is extensively utilized as a critical chiral intermediate in the pharmaceutical sector. Its foremost application lies in the synthesis of side chains for a multitude of widely used semi-synthetic beta-lactam antibiotics. These include essential medicines such as ampicillin, amoxicillin, cefalexin, and cephradine. The specific L-configuration of phenylglycine is integral to the therapeutic efficacy of these antibiotics. Beyond antibiotics, it is also employed in the creation of other chiral drugs, peptide synthesis, and various fine chemical applications requiring stereospecificity.
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