Product Description
D-Proline is the D-enantiomer of the proteinogenic amino acid proline. It is a non-essential amino acid that plays a crucial role as a chiral building block in the synthesis of various pharmaceutical compounds and research chemicals. Unlike its L-proline counterpart, D-Proline is not incorporated into proteins but is highly valued in organic chemistry for its unique stereochemical properties, making it an essential component in the development of novel drugs, including antiviral and anticancer agents.
Product Properties
Property Value CAS Number 344-25-2 Chemical Formula C₅H₉NO₂ Molar Mass 115.13 g/mol Appearance White to off-white crystalline powder Melting Point 228 to 233 °C (442 to 451 °F; 501 to 506 K) (decomposes) Solubility Soluble in water Purity ≥99% Synonyms (R)-Proline, (R)-(-)-Proline, D-2-Pyrrolidinecarboxylic acid Product Usage
D-Proline is widely utilized in several key areas of scientific research and pharmaceutical manufacturing. Its primary applications include:
- Chiral Synthesis: It serves as a fundamental chiral building block and catalyst in asymmetric synthesis to produce enantiomerically pure pharmaceutical intermediates.
- Pharmaceutical Development: D-Proline is a key starting material for synthesizing complex target molecules.
- Peptide Synthesis: Used in the creation of peptidomimetics and synthetic peptides to enhance stability and biological activity. For instance, it’s incorporated into peptide-based drugs to make them resistant to enzymatic degradation.
- Organocatalysis: Employed as an efficient and environmentally friendly organocatalyst in various chemical reactions, such as aldol and Mannich reactions.
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