1. Description
4-(Aminomethyl)benzoic acid (CAS 56-91-7), also known as PAMBA, is an Active Pharmaceutical Ingredient (API) classified as an antifibrinolytic agent. This synthetic amino acid derivative functions by inhibiting plasminogen activation, thereby preventing fibrin breakdown. Its primary benefit is in controlling excessive bleeding in various clinical situations, acting similarly to tranexamic acid.
2. Properties Table
Property Value Product Name 4-(Aminomethyl)benzoic acid CAS Number 56-91-7 Common Synonym PAMBA, p-(Aminomethyl)benzoic acid Chemical Class Antifibrinolytic, Amino Acid Derivative Appearance White or almost white crystalline powder Molecular Formula C8H9NO2 Molecular Weight 151.16g/mol Melting Point >300°C (Decomposes) Solubility Sparingly soluble in water; Practically insoluble in ethanol Purity (Assumed) ≥98.5% (API Grade) 3. Usage
- Active Pharmaceutical Ingredient (API) for manufacturing medications used to reduce excessive bleeding during and after surgical procedures (e.g., cardiac, orthopedic).
- Employed in the treatment of hyperfibrinolytic states and conditions like menorrhagia (heavy menstrual bleeding).
- Used as an antidote in cases of overdose with fibrinolytic (thrombolytic) drugs.
4. Packaging & Transportation
Packaged under GMP conditions in sealed, multi-layer bags within secure fiber or HDPE drums with tamper-evident seals. Transported in compliance with standard chemical regulations; generally classified as non-hazardous (refer to specific SDS).
5. Storage
Store in tightly sealed, light-resistant containers in a dry environment at controlled room temperature (15−25°C). Protect from moisture.
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