4-(Aminomethyl)benzoic acid CAS 56-91-7

1. Description

4-(Aminomethyl)benzoic acid (CAS 56-91-7), also known as PAMBA, is an Active Pharmaceutical Ingredient (API) classified as an antifibrinolytic agent. This synthetic amino acid derivative functions by inhibiting plasminogen activation, thereby preventing fibrin breakdown. Its primary benefit is in controlling excessive bleeding in various clinical situations, acting similarly to tranexamic acid.

2. Properties Table

Property Value
Product Name 4-(Aminomethyl)benzoic acid
CAS Number 56-91-7
Common Synonym PAMBA, p-(Aminomethyl)benzoic acid
Chemical Class Antifibrinolytic, Amino Acid Derivative
Appearance White or almost white crystalline powder
Molecular Formula
Molecular Weight
Melting Point (Decomposes)
Solubility Sparingly soluble in water; Practically insoluble in ethanol
Purity (Assumed) (API Grade)

3. Usage

  • Active Pharmaceutical Ingredient (API) for manufacturing medications used to reduce excessive bleeding during and after surgical procedures (e.g., cardiac, orthopedic).
  • Employed in the treatment of hyperfibrinolytic states and conditions like menorrhagia (heavy menstrual bleeding).
  • Used as an antidote in cases of overdose with fibrinolytic (thrombolytic) drugs.

4. Packaging & Transportation

Packaged under GMP conditions in sealed, multi-layer bags within secure fiber or HDPE drums with tamper-evident seals. Transported in compliance with standard chemical regulations; generally classified as non-hazardous (refer to specific SDS).

5. Storage

Store in tightly sealed, light-resistant containers in a dry environment at controlled room temperature (). Protect from moisture.

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