D-alpha-Tocopheryl succinate CAS 4345-03-3

Description

D-α-Tocopherol succinate, also known as Vitamin E succinate or d-alpha-tocopheryl acid succinate, is a stable, crystalline powder form of natural source Vitamin E (d-alpha-tocopherol). It is created by esterifying d-alpha-tocopherol with succinic acid. This chemical modification results in a highly stable form of Vitamin E that is less prone to oxidation compared to tocopherol itself. D-α-Tocopherol succinate retains the potent antioxidant properties of Vitamin E, protecting cells from oxidative damage caused by free radicals. Its stability and powder form make it particularly suitable for use in dietary supplements (especially tablets and capsules), food fortification, and cosmetic formulations.

Properties

Property	Value
Chemical Name	(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl hydrogen succinate; also known as D-alpha-Tocopheryl acid succinate
Synonyms	Vitamin E succinate, Tocopherol succinate, Alpha-tocopheryl succinate, D-alpha-Tocopheryl acid succinate
CAS Number	4345-03-3
Molecular Formula	C33H54O5
Molecular Weight	Approximately 530.79 g/mol
Appearance	White to off-white crystalline powder
Solubility	Practically insoluble in water; soluble in acetone, ethanol, chloroform, and vegetable oils.
Form	Stable, esterified, powdered form of natural Vitamin E

Usage

D-α-Tocopherol succinate is utilized in various applications due to its stability and antioxidant properties:

• Dietary Supplements: A preferred form of Vitamin E for tablets and hard-shell capsules due to its excellent stability and powder characteristics. It provides antioxidant support for overall health.
• Food Fortification: Used to enrich dry food products, such as cereals, powdered milk, and flour, with a stable source of Vitamin E, enhancing their nutritional profile.
• Cosmetics and Personal Care: Incorporated into skincare products (creams, lotions, sunscreens) for its antioxidant benefits, helping to protect the skin from environmental stressors and improve product stability.
• Pharmaceutical Applications: Used in some pharmaceutical preparations as a stable source of Vitamin E or as an excipient. It has also been researched for its potential anti-cancer properties.
• Animal Nutrition: Added to animal feed to provide a stable source of Vitamin E, crucial for animal health, growth, and immune function.

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