Product Description:
DL-2-(2-Chlorophenyl)glycine, CAS 141196-64-7, is a racemic amino acid derivative featuring an ortho-chlorinated phenyl group attached to the alpha carbon. This compound serves as a crucial intermediate in organic synthesis, primarily for the preparation of pharmaceuticals and other specialized fine chemicals. It is often utilized as a starting material for chiral resolution to obtain specific enantiomers or can be used directly in synthetic processes where a racemic mixture is appropriate.
Product Properties:
Property Value Chemical Name DL-2-(2-Chlorophenyl)glycine IUPAC Name (RS)-2-Amino-2-(2-chlorophenyl)acetic acid Other Names DL-o-Chlorophenylglycine; DL-alpha-Amino-2-chlorophenylacetic acid CAS Number 141196-64-7 Molecular Formula C8H8ClNO2 Molecular Weight 185.61 g/mol Appearance White to off-white crystalline powder Purity Typically ≥98% (supplier dependent) Chirality Racemic (mixture of D and L enantiomers) Melting Point Approximately 190-200 °C (decomposes) (May vary) Solubility Slightly soluble in water; soluble in dilute aqueous acids and alkalis Storage Conditions Store in a cool, dry, well-ventilated place, in a tightly sealed container Product Usage:
DL-2-(2-Chlorophenyl)glycine (CAS 141196-64-7) acts as a key synthetic intermediate, particularly within the pharmaceutical industry. It is a common precursor for producing enantiomerically pure active pharmaceutical ingredients (APIs). This often involves chiral resolution to isolate the desired L-enantiomer (such as L-2-(2-Chlorophenyl)glycine, CAS 141315-50-6), which is a critical building block for the antiplatelet drug. The DL-form is also valuable for research purposes and in syntheses where the specific stereochemistry is not immediately critical or is established later in the synthetic pathway.
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