1. Description
Methyl 4-chloro-3-oxobutanoate, CAS 32807-28-6, is a key beta-keto ester intermediate widely utilized in pharmaceutical synthesis. Its distinct structure, incorporating an alpha-chloro substituent, renders it a highly versatile C4 building block for constructing complex organic molecules, particularly heterocyclic systems prevalent in numerous Active Pharmaceutical Ingredients (APIs). This compound serves as a critical starting material or intermediate in synthetic routes targeting novel therapeutics and specialized fine chemicals.
2. Properties Table
| Property | Value |
| Product Name | Methyl 4-chloro-3-oxobutanoate |
| CAS Number | 32807-28-6 |
| Synonyms | Methyl gamma-chloroacetoacetate, 4-Chloro-3-oxobutanoic acid methyl ester |
| Molecular Formula | |
| Molecular Weight | 150.56 g/mol |
| Appearance | Colorless to pale yellow liquid or low-melting solid |
| Purity | ≥98% |
| Density | approx. 1.27 g/mL (at 20 °C) |
| Boiling Point | approx. 70-75 °C at 5 mmHg (Decomposes at higher temps) |
| Stability | May require refrigerated storage; handle with care |
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