Product Description:
O-Phospho-L-Threonine (CAS 1114-81-4) is a phosphorylated amino acid derivative, specifically of L-Threonine. It is an important biomolecule involved in post-translational modification of proteins, playing a critical role in cell signaling, regulation of enzyme activity, and various other cellular processes. This compound is frequently utilized in biochemical research, proteomics, and drug discovery as a standard, an inhibitor, or a substrate in studies related to kinase activity and phosphorylation pathways.
Product Properties:
Property Value CAS Number 1114-81-4 Molecular Formula C₄H₁₀NO₆P Molecular Weight 199.10 g/mol Appearance White to off-white powder or crystals Solubility Soluble in water Purity Typically ≥98% (varies by supplier) Storage Store at -20°C or 2-8°C, protect from moisture Synonyms Phosphothreonine, L-Threonine phosphate, O-Phosphono-L-threonine Product Usage:
O-Phospho-L-Threonine is extensively used in life science research, particularly in the study of protein phosphorylation and dephosphorylation events, which are fundamental to cellular regulation. Examples of its applications include its use as a substrate for protein phosphatases, an inhibitor for certain kinases, in the development of antibodies specific for phosphorylated threonine residues, and as a standard in mass spectrometry-based proteomics to identify and quantify threonine phosphorylation sites. Pharmaceutical researchers may also investigate its role in disease pathways or as a target for therapeutic intervention.
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