| Molecular Formula | C3H5ClO |
| Molar Mass | 92.52 |
| Density | 1.180g/mLat 20°C(lit.) |
| Melting Point | -48°C |
| Boling Point | 114°C(lit.) |
| Specific Rotation(α) | 34 º (589nm, c=1, MeOH) |
| Flash Point | 33 °C |
| Water Solubility | insoluble |
| Vapor Presure | 10 mm Hg ( 16.6 °C) |
| Vapor Density | 3.29 (vs air) |
| Appearance | Liquid |
| Color | Clear colorless to very pale yellow |
| Merck | 14,3532 |
| BRN | 1420785 |
| Storage Condition | 2-8°C |
| Explosive Limit | 21% |
| Refractive Index | n20/D 1.438(lit.) |
| Physical and Chemical Properties | Boiling point 92-93 °c (360mm Hg). |
| Use | For the synthesis of chiral intermediates and chiral drugs |
R-Epichlorohydrin is an organic compound. The following is a description of the properties, uses, preparation and safety information of R-Epichlorohydrin:
Properties:
R-Epichlorohydrin is a colorless liquid with an irritating odor. It is flammable and miscible with many organic solvents such as alcohols and ethers.
Uses:
R-Epichlorohydrin is mainly used in chemical and pharmaceutical industries. It can be used as a reagent in organic synthesis, such as for the synthesis of ether compounds or as an intermediate in chemical synthesis. It can also be used as a raw material for insecticides, fungicides and preservatives.
Method of Preparation:
A common method of preparation of R-epichlorohydrin is the reaction of 3-chloropropanol with a base to form epichlorohydrin. A base catalyst (such as sodium hydroxide or potassium hydroxide) is often used in this reaction.
Safety Information:
R-Epichlorohydrin is a toxic substance that is irritating to the skin, eyes and respiratory system. Prolonged exposure or inhalation may cause health problems. Wear protective gloves, goggles and clothing when using. Avoid contact with sources of ignition during use and storage and take appropriate fire precautions if necessary. Keep away from open flames, high temperatures and oxidizing agents. Use in a well-ventilated area and avoid inhaling gases or vapors. In case of accidental leakage, appropriate safety measures should be taken immediately to prevent further spreading. In case of accidental contact with skin or eyes, flush immediately with plenty of water and seek medical assistance.
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