Tetradecylthioacetic acid CAS 2921-20-2

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Product Description:

Tetradecylthioacetic acid (TTA), CAS 2921-20-2, is a synthetic fatty acid analogue characterized by a sulfur atom at the beta-position relative to the carboxyl group. This structural modification prevents its beta-oxidation, leading to unique metabolic effects. It is primarily recognized for its role in regulating lipid metabolism and has been investigated for various potential therapeutic applications due to its influence on fatty acid oxidation, glucose utilization, and anti-inflammatory pathways.

Product Properties:

Property Value
Chemical Name Tetradecylthioacetic acid
Abbreviation TTA
CAS Number 2921-20-2
Molecular Formula C₁₆H₃₂O₂S
Molecular Weight 288.49 g/mol
Appearance Typically a white to off-white crystalline powder or solid
Solubility Soluble in organic solvents like ethanol, DMSO, and dimethyl formamide (DMF); sparingly soluble in water.
Melting Point Approximately 56-60 °C (may vary depending on purity)
Purity Available in various purity grades, often >98% for research purposes
Storage Recommended to store in a cool, dry place, away from light, often at -20°C for long-term stability.

Product Usage:

Tetradecylthioacetic acid is primarily utilized in scientific research and pharmaceutical development. Its main applications stem from its ability to modulate lipid and glucose metabolism.

  • Research Chemical: Extensively used in laboratory settings to study fatty acid oxidation, mitochondrial function, insulin sensitivity, and inflammatory responses. For example, researchers might use TTA to investigate its effects on gene expression related to lipid transport in liver cells.
  • Metabolic Disorders: Investigated for potential benefits in conditions like obesity, type 2 diabetes, and dyslipidemia due to its impact on reducing plasma lipid levels and improving glucose tolerance in preclinical models.
  • Anti-inflammatory Studies: Explored for its anti-inflammatory properties, potentially offering therapeutic avenues for inflammatory conditions. An example includes studying its effect on cytokine production in immune cells.
  • Cardiovascular Research: Studied for its potential protective effects on the cardiovascular system, partly through its lipid-lowering actions.

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