Details
Product Name: Trifluoromethanesulfonyl Chloride
CAS Number: 421-83-0
Chemical Formula: CF₃SO₂Cl
Intended Use: Widely used in the synthesis of triflate derivatives and other organic transformations, particularly in pharmaceutical intermediate production.
Safety Consideration: This reagent is corrosive and reacts violently with water. Appropriate safety protocols and personal protective equipment (PPE) are mandatory during handling.
Properties
Below is a table summarizing the key properties:
Property Value Chemical Name Trifluoromethanesulfonyl Chloride CAS Number 421-83-0 Molecular Formula CF₃SO₂Cl Molecular Weight Approximately 168.5 g/mol Appearance Colorless to pale yellow liquid Boiling Point Approximately 65°C* Density ~1.5 g/cm³ Reactivity Highly reactive; moisture sensitive Usage
Trifluoromethanesulfonyl Chloride is primarily employed as an electrophilic reagent in organic synthesis. It is used to introduce triflyl groups into molecules, forming triflate derivatives that serve as versatile intermediates for various chemical transformations. This reagent is especially valuable in pharmaceutical research and industrial chemistry where high purity and controlled reactivity are critical.
Packaging and Transportation
Packaging:
The product is typically supplied in tightly sealed, corrosion-resistant containers, such as glass bottles or specially lined drums, to ensure chemical integrity and safety during storage and transport.Transportation:
The compound is classified as a hazardous material and must be transported in compliance with all relevant regulations. It is shipped under controlled conditions, maintaining temperature and avoiding exposure to moisture, with appropriate labeling and documentation according to international transport standards.Storage
Storage Conditions:
Store in a cool, dry, and well-ventilated area. The product should be kept away from direct sunlight, moisture, and incompatible materials (such as water or strong bases). Ensure that storage facilities meet hazardous material handling standards.Handling:
Due to its highly reactive nature, it is imperative to use proper PPE (gloves, goggles, and lab coats) during handling. Emergency procedures should be in place in case of accidental exposure or spills.
Trifluoromethanesulfonyl Chloride CAS 421-83-0
Trifluoromethanesulfonyl Chloride (CAS 421-83-0): A Comprehensive Overview Introduction Trifluoromethanesulfonyl chloride, often referred to as triflyl chloride, is a specialized chemical compound identified by the CAS