Product Description:
18β-Glycyrrhetinic Acid is a pentacyclic triterpenoid derivative of the beta-amyrin type, primarily obtained from the hydrolysis of glycyrrhizin, which is a major sweet-tasting compound found in licorice root (Glycyrrhiza glabra). It is a white to yellowish crystalline powder known for its various biological activities, including anti-inflammatory, anti-viral, and anti-tumor effects. This compound is widely studied and utilized in pharmaceutical and cosmetic industries.
Product Properties:
Property Value Chemical Formula
C₃₀H₄₆O₄
CAS Number
471-53-4
Molar Mass
470.68 g/mol
Appearance
White to yellowish crystalline powder
Odor
Odorless or slight characteristic odor
Melting Point
Approximately 292-295 °C (558-563 °F; 565-568 K) (decomposes)
Solubility
Practically insoluble in water; soluble in ethanol, chloroform, acetic acid
Optical Rotation
+145° to +165° (in ethanol)
Purity (Typical)
≥98%
Product Usage:
18β-Glycyrrhetinic Acid has diverse applications across several industries due to its significant biological properties:
Pharmaceuticals:
Used as an active ingredient in topical preparations for its anti-inflammatory properties, for example, in creams for dermatitis and eczema.
Investigated for its potential anti-viral effects, including activity against viruses like herpes simplex and hepatitis.
Studied for its hepato-protective and anti-ulcer activities.
Acts as a precursor in the synthesis of other pharmacologically active compounds, such as carbenoxolone.
Cosmetics and Skincare:
Incorporated into skincare products for its soothing, anti-irritant, and skin-conditioning effects; for instance, in lotions for sensitive skin or after-sun products.
Used in formulations aimed at improving skin brightness and reducing redness.
Found in oral care products for its potential benefits in maintaining gum health.
Food Industry:
Sometimes used as a flavoring agent or sweetener enhancer in certain food products, leveraging its origin from licorice.
Research Applications:
Serves as a valuable research chemical for investigating various cellular mechanisms and potential therapeutic targets.
Contact Us Now!
If you need MSDS,TDS or sample testing, please email us at pharm@sinocurechem.com or use the website live chat to get prompt reply.
