1. Description
2,5-Dimethoxytetrahydrofuran, CAS 696-59-3, is a valuable cyclic acetal widely utilized as a key intermediate in pharmaceutical synthesis. It functions primarily as a stable and easily handled precursor to succinaldehyde, which is crucial for constructing various heterocyclic scaffolds like pyrroles, integral components of many Active Pharmaceutical Ingredients (APIs). Its utility as a versatile building block makes it essential for multi-step organic synthesis routes in drug discovery and process development.
2. Properties Table
Property Value Product Name 2,5-Dimethoxytetrahydrofuran CAS Number 696-59-3 Synonyms THF-dimethoxy, Succinaldehyde dimethyl acetal (cyclic) Molecular Formula Molecular Weight 132.16 g/mol Appearance Colorless to pale yellow liquid Purity ≥98% (mixture of cis/trans isomers) Density approx. 1.02 g/mL (at 25 °C) Boiling Point approx. 145-150 °C (at 760 mmHg) Isomer Content Supplied as a mixture of cis and trans isomers
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